Pharmaenergy

11 Responses to “I Am Also Taking Diazepam And Tramadol For My Slipped Discs Pain But Find It Is Doing Nothing!?”

1. Alissa, R.N. says:

   September 4, 2009 at 7:18 pm

   I’ve never heard of anyone having to use suboxone to get off of tramadol.
   Since tramadol isn’t a narcotic, doesn’t make sense that anyone would prescribe suboxone for it. There should be very few physical symptoms from stopping tramadol.
   IT IS ABSOLUTELY NOT A NARCOTIC DynoDikk.
   And, yes, I’m a nurse, and you should probably go back to school. Just because it acts on the opiate receptors, doesn’t mean it’s a narcotic. It’s classified as a “narcotic-like” pain reliever, NOT a narcotic and not an opiate. Get your facts straight before you bash someone who’s educated on the subject.
   So, maybe your pain doctors SHOULD go back to school because every drug guide I’ve looked at – for doctors and nurses alike AND I called and talked to my pain management doctor – ALL SAY “non-opioid analgesic” which means NON NARCOTIC.
   I don’t look like a fool. And it’s pretty clear that Kim K is just DynoDikk under another name. You look like a fool for pushing bogus websites.
2. Kim k says:

   September 4, 2009 at 10:59 pm

   Wow, I guess all of my doctors at the pain management clinic should go back to school too, they for some strange reason consider ultram a dangerous narcotic that requires careful supervision. Hon, everyone makes mistakes, you only look like a fool when faced with published data you continue to refuse to admit error. As you’re convinced you know more than doctors, scientists and the DEA maybe you should publish something. No, not in a comic book, in a medical journal.
   People with no medical education should be banned from using the site for posting under false pretenses when they say they’re something that they aren’t. If you used to be a nurse who has not continued her education you shouldn’t call yourself a nurse, call yourself a retired nurse if that’s the case. Misrepresentation just tells us that you feel the need to make up stories about your “qualifications”. this is a danger of the internet, anyone can say they’re anything and unfortunately people may believe them and actually get hurt because of the stories made up in order to sound more educated than you are. It’s sad that your pride is more important to you than people’s health and well being.
   In 1995 the maker of Ultram agreed that tramadol shared nothing with narcotic substances but the propaganda put out by them was discredited a decade ago.
   Text below from: http://www.deadiversion.usdoj.gov/drugs_…
   “…Although the company initially claimed that this substance produced only very weak narcotic effects, current data demonstrates that opioid activity is the overriding contributor to the drug’s pharmacological activity. Because of inadequate product labeling and lack of established abuse potential, many physicians felt this drug was safe to prescribe to recovering narcotic addicts and to known narcotic abusers. As a consequence, numerous reports of abuse and dependence have been received.” and “…“ULTRAM may induce psychic and physical dependence of the morphine-type (µ-opioid). Dependence and abuse, including drug-seeking behavior and taking illicit actions to obtain the drug are not limited to those patients with prior history of opioid dependence. The risk in patients with substance abuse has been observed to be higher. ULTRAM is associated with craving and tolerance development. Withdrawal symptoms may occur if ULTRAM is discontinued abruptly.”
3. DynoDiKk says:

   September 5, 2009 at 5:55 am

   Well MISS Alissa RN, little physical symptoms after taking Ultram, Hmmmm, and your a nurse and says that is not a narcotic? It is an opiate, it works on MU-1 opiate receptors.
   (CHANGE YOUR ANSWER YOUR GONNA LOOK LIKE A FOOL!) IT IS A MILD OPIATE! Holy GOD!! HOW DON’T YOU KNOW THIS???? Type in Ultram Sucks on the computer on google and see the horrible withdrawal people are having. I weaned off 200 mg’s of Methadone a day and Ultram was worse than that, worse than OxyContins! FUNNY and they said it was non addicting and not an opiate. Type in my name on google followed by Ultram and read. I don’t know how anyone can say this drug is not a narcotic, it is, the evidence on the internet is overwhelming. Case closed! SO it does not have the typical structure of one, either DOES FENTANYL! YOUR WRONG! And the text you wrote it in is misleading! IT IS AN OPIATE!
   Drugs and Chemicals of Concern
   ————————————–…
   TRAMADOL
   (Trade Names: Ultram®, Ultracet®)
   June 2009
   DEA/OD/ODE
   Introduction:
   Tramadol was approved for marketing as a noncontrolled analgesic in 1995 under the trade name of Ultram®. Although the company initially claimed that this substance produced only very weak narcotic effects, recent data demonstrate that opioid activity is the overriding contributor to the drug’s pharmacological activity. Because of inadequate product labeling and lack of established abuse potential, many physicians felt this drug was safe to prescribe to recovering narcotic addicts and to known narcotic abusers. As a consequence, numerous reports of abuse and dependence have been received.
   Licit Uses:
   Tramadol is approved for the treatment of moderate to moderately severe pain in adults. Although the Department of Health and Human Services has not recommended the scheduling of this substance in the Controlled Substances Act (CSA), a requirement necessary for DEA to place a substance under control, the Food and Drug Administration (FDA) has required the manufacturer of Ultram® to inform physicians about recent abuse data. The approved labeling has been modified on three separate occasions to include new information under the “Drug Abuse and Dependence” section. The labeling currently contains the following language:
   “ULTRAM may induce psychic and physical dependence of the morphine-type (µ-opioid). Dependence and abuse, including drug-seeking behavior and taking illicit actions to obtain the drug are not limited to those patients with prior history of opioid dependence. The risk in patients with substance abuse has been observed to be higher. ULTRAM is associated with craving and tolerance development. Withdrawal symptoms may occur if ULTRAM is discontinued abruptly.”
   According to the IMS Health National Prescription Audit Plusâ„¢, retailers dispensed 26.6 million tramadol prescriptions in 2008.
   Chemistry/Pharmacology:
   Tramadol is a novel analgesic having both opiate agonist activity and monoamine reuptake inhibition that contribute to its analgesic efficacy. Opioid activity is due to both the parent compound and the more active O-desmethylated metabolite. Tramadol acts on the monoamine reuptake systems by inhibiting the reuptake into nerve terminals of both norepinephrine and serotonin.
   Apart from analgesia, tramadol may produce a number of symptoms including dizziness, somnolence, nausea, and constipation similar to other opioids. High doses of tramadol, often in combination monoamine oxidase (MAO) inhibitors or serotonin-selective reuptake inhibitors (SSRIs), have been associated with a serotonin syndrome consisting of convulsions, hyperthermia, muscle rigidity and pain.
   Tramadol is well absorbed orally. It can be administered in 50 to 100 mg tablets as needed for pain relief every 4 to 6 hours, not to exceed 400 mg/day. Seizures have occurred in patients taking recommended doses but are more likely at high doses associated with abuse of this medication. Tolerance, dependence and addiction to tramadol have been demonstrated. Abrupt cessation from tramadol has been associated with two types of withdrawal syndromes. One is typical of opioid drugs with flu-like symptoms, restlessness and drug craving. This type of withdrawal syndrome is encountered in about 90 percent of cases of withdrawal from tramadol. Another withdrawal syndrome (encountered in about 10 percent of cases of tramadol withdrawal) is atypical of opioids and is associated with hallucinations, paranoia, extreme anxiety, panic attacks, confusion, and numbness and tingling in the extremities.
   Abuse and Diversion:
   Tramadol is most commonly abused by narcotic addicts, chronic pain patients, and health professionals.
   According the American Association of Poison Control Centers, there were 5,965 tramadol case mentions and 3,247 single exposures (2 deaths) in 2006. In 2007, 7,500 case mentions and 4,053 single exposures (1 death) were associated with tramadol. In 2008, the National Forensic Laboratory System (NFLIS) reported that law enforcement submitted 15 tramadol drug items/exhibits to DEA laboratories and 1,055 drug items/exhibits to state and local forensic laboratories for analysis.
   Controlled Status:
   Tramadol is not currently controlled under the CSA; however, Arkansas and Kentucky have designated tramadol as a schedule IV drug under state law.
   Comments and additional information are welcomed by the Drug and Chemical Evaluation Section, FAX 202-353-1263 or telephone 202-307-7183.
   Tramadol even shows up positve in an opiate drug test. Opiate metabolites are present in urine when a person takes just tramadol. That is close enough, HUH????
   But not everone gets dependant on ultram.
   here is some examples;
   Ultram withdrawal – Addiction: Substance Abuse – MedHelpTH E WITHDRAWS I GO THRU ARE HORRIBLE FROM ULTRAM I TAKE 20 A DAY IVE LOWERED THAT NOW … hated it. am i in for deep **** and what are my options for withdrawal from ultram. my doc …
   http://www.medhelp.org/posts/Addiction-Substa… · Cached pageReport on Ultram Side Effects and Usage by AskDocWebI know also that quitting it “cold turkey” is horrible: absolute sleeplessness … Subj: Ultram withdrawal Date: 7/28/2003 I have been taking Ultram for 2 years due to 2 torn …
   http://www.askdocweb.com/ultram.html · Cached pageQuitting Ultram Tramadol. Ultram withdrawal symptoms.I was addicted to Ultram, and also to vicodin, and in my opinion the withdrawal and addiction to Ultram … I am having horrible withdrawls I have been taking tylonal 3 for years and go …
   hubpages.com/hub/Quitting-Ultram · Cached pageUltram withdrawal – Addiction: Substance Abuse – MedHelpUltram is horrible horrible horrible horrible. I’ve just come off tramadol (Ultram is … I feel for you and I have been on the drugs you have mentioned and yes Ultram withdrawal …
   http://www.medhelp.org/posts/Addiction-Substa… · Cached pageULTRAM: Side effects, ratings, and patient commentsConsumer ratings reports for ultram. Includes patient rankings on scale of 1-5 … She has gone off & is suffering horrible withdrawal symptoms, such as agitation, depression …
   http://www.askapatient.com/viewrating.asp?dru… · Cached pageTramadol Withdrawal? Detox from Tramadol/Ultram Addiction & AbuseWithdrawal from this drug is one of the most horrible and unbearable to experience, comparable to that of … Tramadol/Ultram Withdrawal Symptoms Tramadol/Ultram withdrawal can be a …
   http://www.rapiddrugdetox.com/detox-facts–dr… · Cached pageRe: Ultram withdrawal » femliteIn reply to Re: Ultram withdrawal » Ame Sans Vie, posted by femlite on October 13, 2003, at 14:51:12. It seems to be the cause of a really horrible fibromyalgia flare-up I’m having …
   dr-bob.securesites.com/babble/20031010… · Cached pageFeedback on Ultram Side Effects and Usage page 14I am down to three Ultram a day, from taking the max which is 8 50mg pills. The withdrawal from it is horrible. My blood pressure spikes, and I have to take it just because of that
   http://www.askdocweb.com/ultram14.html · Cached pageMyanmarMp3.netAnd withdrawal when naproxen alone with other serotonergic agents. A horrible nights sleep! In occur if ULTRAM is 400 mg day in the range of ?-opioid receptor antagonist naloxone.
   http://www.myanmarmp3.net/readnews.aspx?NewsI… · Cached pageRe: Ultram Er and withdrawal-Except for I went through horrible anxiety attacks also. Your doctor is WRONG when … Re: Ultram Er and withdrawal- » spriggy Quintal 5/1/07; Re: Ultram Er and withdrawal-crenshaw387 5/2/07
   dr-bob.securesites.com/babble/20070426… · Cached pagePagination
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   and to those that say it is not a narcotic!
   (+/-)-Tramadol is a synthetic analogue of codeine. It is a central analgesic with a low affinity for opioid receptors. Its selectivity for mu receptors has recently been demonstrated, and the M1 metabolite of tramadol, produced by liver O-demethylation, shows a higher affinity for opioid receptors than the parent drug. The rate of production of this M1 derivative (O-demethyl tramadol), is influenced by a polymorphic isoenzyme of the debrisoquine-type, cytochrome P450 2D6 (CYP2D6). Nevertheless, this affinity for mu receptors of the CNS remains low, being 6000 times lower than that of morphine. Moreover, and in contrast to other opioids, the analgesic action of tramadol is only partially inhibited by the opioid antagonist naloxone, which suggests the existence of another mechanism of action. This was demonstrated by the discovery of a monoaminergic activity that inhibits noradrenaline (norepinephrine) and serotonin (5-hydroxytryptamine; 5-HT) reuptake, making a significant contribution to the analgesic action by blocking nocice
4. mhchicet says:

   November 3, 2009 at 9:58 am

   You didn’t say how long you’ve been taking the meds….sometimes it takes a little while. What else are you doing? Are you going to physical therapy? What position are you sleeping in at night? Did you hurt yourself on the job? If you did, they may not be able to dismiss you because they are responsible for your injury. I would speak to your doctor and see what your options are. Most doctors try other forms of treatment before back surgery…or any kind of surgery. In March of 2007 I had a total knee replacement. My knee cap separated from my knee/bones. They didn’t operate right away. I went through pain for over a year while they tried other medical treatments and used surgery as a last option. Unfortunately….once you have an injury like this it is possible that you will develop arthritis in the back.
5. Buy Cold Sore Freedom says:

   November 3, 2009 at 4:42 pm

   well it depends what dose of tramadol and diazepam you are on, without knowing that its kind of hard to tell. have you seen an osteopath?
6. tos.p says:

   November 3, 2009 at 6:29 pm

   http://www.all-healthtalk.com/obese-smokers-at-higher-risk-of-death.html
   It will solve your problem
   I wish you good luck
7. willoug says:

   November 3, 2009 at 9:07 pm

   i would grow a clone and download your brainwave patterns into it, then donate your old body to the starving in africa
8. Charles S says:

   November 4, 2009 at 3:40 am

   I thought that diazepam was a relaxant and used to treat anxiety. If my recollection is right, it may be that the relaxant properties of the drug help the discs return to their correct position. I assume that tramadol is the painkiller because I’ve not heard of that drug.
   Some people have a higher threshold before pain relief takes effect. For a short-term, it wouldn’t harm you to take more than the recommended maximum dose of aspirin or ibuprofen. Aspirin usually has a maximum recommended dose of 900mg for an adult. You could try 1200mg (4 tablets) or even 1500mg (5 tablets) with little risk, provided your stomach is healthy. It might be best to take it in the form of Alka Seltzer as this contains an ingredient to counter the bad stomach effect of aspirin. You can also take the standard dose of paracetamol at the same time. DO NOT EXCEED the recommended dose of paracetamol. It is highly toxic in excess.
   Only take a mega dose of aspirin once without consulting your doctor but it’s better to consult the doctor first if you can. The main risks of aspirin in excess are bleeding, stomach hyperacidity and very small risk of stomach wall rupture. Alka Seltzer counters the stomach risks to some extent. If you find that this counters your pain, the doctor may feel the risk is worthwhile to prescribe aspirin at a high dose. Aspirin is not that toxic in itself but the side effects of bleeding can lead to death (12-14 tablets is usually lethal). It may be that the doctor can prescribe higher doses of aspirin with a coagulating drug.
9. danielte says:

   November 4, 2009 at 10:02 am

   First of all when diazepam was originally produced it was marketed as a pain killer/muscle relaxer. but later thru extensive testing found out thatit was better served as anti-anxiety medications. now to the tramodol it is a “Narcotic” LIKE Pain medication that in my opinion should only be used for a slight headache in fact you would be better off taking naproxen. My advice to you is make a doctors appointment asap and when you do tell him that the tramodol is not relieving the pain at all. Do not volunteer any information about what kind of pain medication has worked for you in the past but if he comes out right and asks you then tell him either hydrocodine or percocets has given you relief from the pain and helped you sleep good at night
10. Spyware Blocking says:

    November 4, 2009 at 2:51 pm

    I suffer with something that is similar, I have four discs that have collapsed on both sides of the spine.I was refer ed to a specialist who told me that I had got degenerative disc decease and that it would unwise to operate on.So I am still suffering. Ten years ago my GP sent me to see a specialist at the spinal foundation in OLDHAM they do have a web site. Anyway the told me that it was possible to operate as they use a side cutting laser which cuts away the part of the disc that is causing the pain.I was able to have an operation which did get rid of the pain on one side but I would need more operations 7 in all but the N H S decided that they was no longer going to fund the treatment for me. So I am still suffering. The pain killers that I have are Co-codamol 30/500 which I can take up to 8 a day and Tramadol which I have found to help me at night. They don’t take the pain away but they do take the off it. I myself use a wheelchair when I go out if I did not I would be on my back in bed. Of course this has made it so I can no longer go to work since I was an electrician. I do have other medical problems as well which also stops me from working.
    I give you my best regards and hope things do get better for you .One thing about Diclofenic is they take a while to get into your system.
11. Intake says:

    November 4, 2009 at 8:03 pm

    DIAZEPAM is VALUM, why are u taking a ANTI ANexity pill ?
    Tramadol is a Bull **** medication that doesnt work.. if u have slipped disc pains, u should be taking Morphine/ oxycodone/ hydrocodone.. maybe even Methadol.. some kind of Long Lasting Medication..
    Tramdadol is a synthetic narcotic pain killer that doesnt work. i tried it.. taking 300 mg a DAY for hip and back pain..
    Go back to the doctor and tell him u need Muscle Relaxants, like SOMA .. or the none narcotic brother medication FLEXORIL/FLEXORAL.. those are muscle relaxants.. VALUM is NOT and im not sure why u are taking it.. unless u have anexity or panic attacks..
    GO back to the doctors office and ask WHY are u taking anti aniexty medication are a bad disc.. and them him that tramadol isnt working.. and u want to be switched to something else.. like a LONG actings/ sustained Release type of Pain Killer.. Dont say names.. cause then there thinking ur Drug seeking