What Are The Stages Of Death In Paracetamol Overdose?
What happens, and in what order?
(I’m not intending to do anything by the way, I’m a happy person!)
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Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported.
Hello,
(ANS) I used to work some years ago on the Intensive Care Unit at a major NHS hospital here in Leeds. (I was the units database manager but I come from a medical family) We used to deal with a large number of paracetamol overdose cases because the unit was specially set up for them.
No.1 With paracetamol overdose cases its hard to know how a person is going to react because there are a large number of variable factors involved. Such as the age, weight of the person, how many tablets they ingested, and how long ago they were consumed. Were the tablets consumed with other drugs or by themselves, or with alcohol,etc.
No.2 if caught very early a Paracetamol OD can be treated with antidotes which prevent the worst damage. And protect the body from organ damage but its only possible in a few cases and when only a lowish dose has been taken.
No.3 With OD liver damage is the major problem & liver damage has all sorts of complex inter related symptoms in terms of how to treate someone. When its too late to prevent the worst effects patients often go into multiple organ failure. Most patients bleed to death and die from acute liver failure. i.e. the liver shuts down.
No.4 Perhaps the most horrifying aspect of this kind of OD is that some patients having taken an OD & having been taken to hospital think they will survive. Only to be told by the doctors that death is certain & that nothing can prevent it now. So even were the OD was really a cry for help the outcome is certain death.
No.5 the person goes into liver failure>>then often bleeding>>multi organ failure. Only a fast liver transplant can sometimes prevent death but even so liver transplantation can go wrong and livers can be rejected. Even if a liver transplant is successful the person would be on anti rejection drugs for life post operatively.
Ivan
You end up in liver failure… often people take OD leave it too long think they are ok, only to have liver failure a day or so later.. I have seen someone wake up on a medical ward “relieved” that she hadn’t actually died from the OD, only for her to die two days later because of liver failure…
Im not sure but i think you have to take over 100 to do anything like that
i think maybe the brain would swell, making you very sick, dizzy, blured vision, then you would collapse and not know much about it
PAIN, PAIN, PAIN AND MORE PAIN
Pain followed by extreme pain then death
One of the most horrific ways to go with regards to pain………. that should put anyone off