How Is Paracetamol Synthesized On An Industrial Scale?

What Catalysts are used (if any) and what are the products (+ paracetamol) as well as and reactants! Need to know on an industrial scale, which process is most viable! Thanks! How long does it take and how is it transported? And any quality control procedures used! Basically any information would be welcome!
Thanks alot!.

One thought to “How Is Paracetamol Synthesized On An Industrial Scale?”

  1. Paracetamol ( p-OH acetanilide ) is synthesized from p-amino phenol and acetic anhydride
    2HO-PHE-NH2 + CH3CO-O-COCH3—— 2 HO-PHE-NHCOCH3 + H2O
    acetic anhydride can be made by dehydration of acetic acid over a catalyst at elevated temperatures. The p-amino phenol is made from p-nitro phenol by reduction with Sn/HCl or NaBH4, or other reducing agents.

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